Original Adidas women's football shirt Real Madrid CF 2015/16

Under new manager Rafael Benítez, Real Madrid remained unbeaten in the league until a 3–2 loss at Sevilla on the matchday 11. Perhaps, his reign is best remembered by multiple lopsided wins achieved both in La Liga and the Champions League (6–0 vs Espanyol, 8–0 vs Malmö, 10–2 vs Rayo Vallecano and others). In the Copa del Rey round of 32, Real accidentally fielded an ineligible player, who was suspended from the previous season (when he was representing a different team), resulting in the team's controversial disqualification from the tournament by the competition judge despite protests from President Pérez. In the meantime, Real comfortably topped their UCL group with 16 points and a +16 goal difference. Benítez was relieved of his duties mid-season, following allegations of unpopularity with supporters, displeasure with players and a failure to get good results against top teams. Benítez's departure was announced along with the promotion of Zinedine Zidane to his first head coaching role. Under Zidane, Madrid managed to turn the odds in its favor, ultimately winning the Champions League, something no one expected. The notable results include a 2–1 away victory over reigning treble winners Barcelona, who were on a record-breaking winning streak, a fantastic comeback against Wolfsburg in the Champions League quarter-finals (after losing the away game 0–2, Madrid erased the deficit and won 3–0 at home, courtesy of a Cristiano Ronaldo hat-trick), as well as a 12-game winning streak to conclude the league campaign, meaning Real finished second, with 90 points and just one point behind champions Barcelona, coming agonizingly close to clinching the title and overcoming a 12-point deficit in the process. Finally, on 28 May, Real Madrid's eleventh Champions League title was won thanks to a 5–3 penalty shoot-out victory over rivals Atlético Madrid after a 1–1 draw in the final, with the achievement being termed "La Undécima".

This season was the first since 1998–99 without legendary goalkeeper Iker Casillas, who departed to Porto. Casillas spent 16 years with the club having won 19 trophies altogether.